ALX Oncology Announces Initiation of Phase 2 Investigator-Sponsored Trial of Neoadjuvant Radiation and Evorpacept in Combination with Pembrolizumab in Patients with Untreated HPV-Mediated ...
ALX Oncology Holdings Inc. (ALXO)
Company Research
Source: Yahoo! Finance
immuno-oncology company developing therapies that block the CD47 immune checkpoint pathway, today announced the initiation of a Phase 2 investigator-sponsored trial (“IST”) of neoadjuvant radiation and evorpacept, a next-generation CD47 blocker, in combination KEYTRUDA ® (pembrolizumab) in patients with previously untreated and early-stage locally advanced, resectable, human papillomavirus-mediated oropharyngeal cancer (“HPVOC”). This multi-center, single-arm, open-label Phase 2 IST is being led by Joseph A. Califano III, M.D., Director of the Hanna and Mark Gleiberman Head and Neck Cancer Center at the University of California, San Diego ( NCT05787639 “Despite standard immune and chemoradiation neoadjuvant therapies for patients with locoregionally advanced HPVOC, associated severe toxicities and lack of durable responses underscore the need for novel therapies” said Dr. Califano. “Early clinical studies with immunotherapy in combination with stereotactic body radiation therapy, wh
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ALXO
News
- ALX Oncology Reports First Quarter 2024 Financial Results and Provides Corporate Update [Yahoo! Finance]Yahoo! Finance
- ALX Oncology Reports First Quarter 2024 Financial Results and Provides Corporate UpdateGlobeNewswire
- ALX Oncology Appoints Allison Dillon as Chief Business Officer [Yahoo! Finance]Yahoo! Finance
- ALX Oncology Appoints Allison Dillon as Chief Business OfficerGlobeNewswire
- ALX Oncology Announces Initiation of Phase 2 Investigator-Sponsored Trial of Neoadjuvant Radiation and Evorpacept in Combination with Pembrolizumab in Patients with Untreated HPV-Mediated Oropharyngeal CancerGlobeNewswire
ALXO
Earnings
- 5/9/24 - Beat
ALXO
Sec Filings
- 5/15/24 - Form 4
- 5/13/24 - Form 144
- 5/9/24 - Form 10-Q
- ALXO's page on the SEC website