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Stock impact report

ALX Oncology Has 'Elevated Valuation' - Analyst Downgrades Stock, Highlights Need For Development De-Risking Beyond Gastric Cancer [Yahoo! Finance]

ALX Oncology Holdings Inc. (ALXO) 
Company Research Source: Yahoo! Finance
As of December 31, 2023, cash equivalents and investments were $218.1 million. The company says the cash balance and the ability to draw down an additional $40 million of its term loan are sufficient to fund planned operations into early 2026 In October 2023, ALX Oncology released prespecified interim Phase 2 data from its ASPEN-06 trial of evorpacept plus trastuzumab, Cyramza (ramucirumab), and paclitaxel for HER2-positive gastric/ gastroesophageal junction cancer A confirmed overall response rate (ORR) of 52% was demonstrated for evorpacept in combination with trastuzumab + Cyramza + paclitaxel compared to 22% for the control group of trastuzumab + Cyramza + paclitaxel. Stifel has downgraded ALX Oncology, saying that the evaluation of ALX Oncology's CD47 blocker, evorpacept, suggests that its value is currently justified for the HER2+ gastric cancer development opportunity. The analyst downgrades ALX Oncology stock from Buy to Hold. Stifel notes that the assessment is c Show less Read more
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