ALX Oncology Holdings Inc. Q4 2025 Earnings Call Summary [Yahoo! Finance]
ALX Oncology Holdings Inc. (ALXO)
Company Research
Source: Yahoo! Finance
ALX Oncology Holdings Inc. Q4 2025 Earnings Call Summary - Moby Strategic Shift to Precision Oncology Management is transitioning evorpicept (EVO) to a targeted oncology approach after clinical data identified CD47 as a critical predictive biomarker for durable response. Performance in HER2-positive gastric and breast cancer trials demonstrated that clinical benefit is largely restricted to patients overexpressing CD47, validating the drug's mechanism in combination with Fc-active antibodies. The company achieved a strategic financing of $150,000,000 in February 2026, extending the cash runway through 2028 and supporting expanded clinical cohorts. Operational focus has narrowed to two core programs: advancing EVO in breast cancer and escalating doses for the EGFR-targeted ADC, ALX 2004. The 'R-squared' combination in non-Hodgkin's lymphoma yielded a 92% complete response rate, nearly doubling benchmark results and reinforcing EVO's potential in hematologic malignancies.
Show less
Read more
Impact Snapshot
Event Time:
ALXO
Last Price
Price Change
Price Change%
Volume Shares
Max Up
Max Down
%
Volume Ratio
Performance Comparison
Updated
|
Event Day
Stock performance from the time of news release until the following 4pm ET market close
|
Last price at news event
|
Since Event
Multi-day stock performance from the time of the news release
|
|---|---|---|
|
EVENT DAY
Stock performance from the time of news release until the following 4pm ET market close
|
LAST
PRICE AT NEWS EVENT |
SINCE EVENT
Multi-day stock performance from the time of the news release
|
| Last Price | ||
| VWAP | ||
|
High:
|
Max Up |
High:
|
|
Low:
|
Max Down |
Low:
|
|
%
|
Post news range |
%
|
|
|
Price change |
|
|
|
Price Change Percentage |
|
|
|
S&P 500 (SPX) |
|
|
%
|
Volume ratio |
%
|
| Volume | ||
| Ticks | ||
|
|
Avg transaction size |
|
Don't Miss Out On The Next BIG Stock Move
Event day
Event Day Chart will not be displayed beyond 90-day period of the event
Performance since event
Time And Velocity Analysis
Be the first to know
Opt in for alerts from News Quantifed
Sign Up Today
Opt-in for
ALXO alerts
Learn More With NQ
Reading the Impact Report
Help Me Understand This Data
Help Me Understand This Data
How NQ Works
What is news-based trading?
And why is it so successful?
And why is it so successful?
Movers & Shakers
The biggest gainers and losers and WHY it moved
ALXO alerts
High impacting ALX Oncology Holdings Inc. news events
Weekly update
A roundup of the hottest topics
ALXO
News
- ALX Oncology Highlights $150M Raise, Evorpacept Breast Cancer Push and EGFR ADC ALX2004 Update [Yahoo! Finance]Yahoo! Finance
- ALX Oncology: Evorpacept For ASPEN-09 Presses On With 2 Key Milestones [Seeking Alpha]Seeking Alpha
- ALX Oncology outlines pivotal trial readiness by end of 2026 with expanded ASPEN-09 study and $150M financing [Seeking Alpha]Seeking Alpha
- ALX Oncology Holdings Inc (ALXO) Q4 2025 Earnings Call Highlights: Strong Clinical Progress and ... [Yahoo! Finance]Yahoo! Finance
- ALX Oncology Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Corporate Update [Yahoo! Finance]Yahoo! Finance
ALXO
Earnings
- 2/27/26 - Miss
ALXO
Sec Filings
- 3/5/26 - Form 4
- 3/5/26 - Form 3
- 2/27/26 - Form 8-K
- ALXO's page on the SEC website