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-0.000180786057779265 0.000180786057779265 -0.000162707452001154 0.000108471634667641 0.00231406153957402 0.00294681274180134 0.00386882163647537 0.00122934519289884
Stock impact report

ACELYRIN (SLRN) Up on Data From Thyroid Eye Disease Study [Yahoo! Finance]

Amgen Inc. (AMGN) 
Last amgen inc. earnings: 4/30 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: investors.amgen.com
Company Research Source: Yahoo! Finance
its humanized IgG1 monoclonal antibody, lonigutamab, for the treatment of thyroid eye disease (TED). Lonigutamab is delivered subcutaneously (SC) that targets the insulin-like growth factor-1 receptor (IGF-1R), a proved mechanism of action in the treatment of TED. Data from the ongoing phase I/II study showed that treatment with lonigutamab led to improvements in proptosis, clinical activity score and diplopia versus placebo at the first measurement, within three weeks following the first SC dose. Overall, treatment with lonigutamab was generally well-tolerated with no serious adverse side effects being reported in the given patient population. With the proof of concept now achieved for lonigutamab in the treatment of TED, SLRN remains focused to initiate a phase IIb/III study on the candidate in the second half of 2024. Shares of ACELYRIN have plunged 64.6% in the past year compared with the industry's decline of 6.6%. Image Source: Zacks Investment Research TED is a ch Show less Read more
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