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Stock impact report

ALMS Surges as Envudeucitinib Meets Goals in Plaque Psoriasis Studies [Yahoo! Finance]

Amgen Inc. (AMGN) 
Last amgen inc. earnings: 4/30 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: investors.amgen.com
Company Research Source: Yahoo! Finance
ONWARD2 — which evaluated its pipeline candidate, envudeucitinib, for treating patients with moderate-to-severe plaque psoriasis, a chronic autoimmune skin disease. Both the ONWARD1 and ONWARD2 studies met all primary and secondary endpoints with high statistical significance in patients with moderate-to-severe plaque psoriasis. Treatment with envudeucitinib led to superior skin clearance versus placebo on the co-primary endpoints of Psoriasis Area and Severity Index (PASI) 75 and static Physician's Global Assessment (sPGA) 0/1 at week 16 in both studies. On average, in the ONWARD1 and ONWARD2 studies, 74% of patients achieved PASI 75 and 59% achieved sPGA 0/1, with responses improving over time. At week 24, across both studies, about 65% of patients achieved PASI 90 and more than 40% achieved PASI 100. Treatment with envudeucitinib was generally well tolerated through week 24 in both the ONWARD1 and ONWARD2 studies. Treatment with envudeucitinib also achieved superior skin cl Show less Read more
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