Amylyx Nominates AMX0318 as Long-Acting GLP-1 Candidate for Rare Endocrine Disorders [Yahoo! Finance]
Amylyx Pharmaceuticals, Inc. (AMLX)
Company Research
Source: Yahoo! Finance
the nomination of AMX0318 as its newest development candidate. Identified through a strategic collaboration with Gubra A/S, AMX0318 is a novel, long-acting glucagon-like peptide-1/GLP-1 receptor antagonist designed to treat post-bariatric hypoglycemia/PBH and other rare diseases. The development of AMX0318 utilized Gubra's proprietary streaMLine platform, which is an AI-driven technology used to optimize peptide candidates. Amylyx plans to initiate IND-enabling studies for AMX0318 later in 2026, with a target of filing an IND application in 2027. This new program complements Amylyx's existing lead candidate, avexitide, which is currently being evaluated in the pivotal Phase 3 LUCIDITY trial for PBH. The company expects to finish recruitment for the LUCIDITY trial in Q1 2026 and anticipates a topline data readout in Q3 2026. Earlier on December 19, Bank of America lowered the firm's price target on Amylyx to $15 from $16, while keeping a Buy rating on the shares. Following Amylyx's
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News
- Amylyx Pharmaceuticals (AMLX) Valuation Check As New GLP-1 Candidate AMX0318 Enters Development Stage [Yahoo! Finance]Yahoo! Finance
- Amylyx Pharmaceuticals (AMLX) Announces the Selection of AMX0318 as Development Candidate for PBH and Other Rare Diseases [Yahoo! Finance]Yahoo! Finance
- Amylyx Pharmaceuticals Announces Nomination of AMX0318 as a Novel, Long-Acting GLP-1 Receptor Antagonist Development Candidate, Identified in Collaboration with Gubra A/SBusiness Wire
- Amylyx Pharmaceuticals (NASDAQ:AMLX) was downgraded by analysts at <a style="font-weight:bold" href="https://www.wallstreetzen.com/newsletters/zen-ratings?ticker=AMLX&utm_campaign=getratings&utm_medium=online&utm_source=MarketBeat">Wall MarketBeat
- Is Early AMX0114 Safety Data Altering The Investment Case For Amylyx Pharmaceuticals (AMLX)? [Yahoo! Finance]Yahoo! Finance
AMLX
Earnings
- 11/6/25 - Beat
AMLX
Sec Filings
- 1/16/26 - Form 144
- 1/16/26 - Form 144
- 1/15/26 - Form 144
- AMLX's page on the SEC website