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0.0271903323262839 0.0271903323262839 0.0271903323262839 0.0271903323262839 0.0332326283987915 0.0332326283987915 0.0332326283987915 -0.0332326283987915
Stock impact report

Adlai Nortye to Present Short Talk on AN4035 Preclinical Results at AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics

Adlai Nortye Ltd. - American Depositary Shares (ANL) 
Company Research Source: GlobeNewswire
SINGAPORE and NORTH BRUNSWICK, N.J. and HANGZHOU, China, Oct. 22, 2025 (GLOBE NEWSWIRE) -- Adlai Nortye Ltd. (NASDAQ: ANL) (the “Company” or “Adlai Nortye”), a clinical-stage biotechnology company focused on the development of innovative cancer therapies, today announced that it will deliver an oral presentation at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held from October 22-26, 2025, in Boston, MA. Key highlights of the presentation include: AN4035 demonstrated strong intracellular payload retention, driving nanomolar to picomolar cytotoxicity in CEACAM5-positive/RAS-addicted cancer cell lines, along with a potent bystander-killing effectAN4035 induced deep regression in CEACAM5-positive/RAS-addicted CDX and PDX models, achieving a 73% objective response rate in a patient-derived xenograft trial (N=26)AN4035 exhibited a favorable preliminary toxicology profile in cynomolgus monkeys Tricomplex pan-RAS(ON) inhibitors currently in c Show less Read more
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