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Stock impact report

Annexon Investor Day: ANX007 Targets C1q in Dry AMD GA as Phase III Readout Nears Q4 [Yahoo! Finance]

Annexon, Inc. - common stock (ANNX) 
Company Research Source: Yahoo! Finance
and visual function, a strategy Annexon argues is distinct from approved downstream C3/C5 inhibitors that target lesion/RPE atrophy. In the 270-patient Phase II ARCHER study the primary FAF lesion-growth endpoint was not met, but OCT showed reduced ellipsoid-zone loss (up to 27–59% in nearer-foveal regions) and functional analyses reported a strong signal for vision protection (reported ~73% risk reduction for confirmed 15-letter BCVA loss with monthly dosing), with no new major safety signals. The global ARCHER II Phase III (659 patients, 2:1 randomization) incorporated protocol changes to enrich events—excluding very low baseline vision, increasing subfoveal lesion representation, and extending the primary endpoint to 15 months—and topline results are expected in Q4 this year. Interested in Annexon, Inc.? Here are five stocks we like better. Annexon (NASDAQ:ANNX) used its Investor Day presentation to outline the scientific rationale and clinical progress for vonoprument (ANX Show less Read more
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