Annovis Announces Publication That Supports Understanding of Buntanetap's Mechanism of Action in Humans [Yahoo! Finance]
Annovis Bio, Inc. (ANVS)
Company Research
Source: Yahoo! Finance
MALVERN, Pa., April 01, 2024 (GLOBE NEWSWIRE) -- Annovis Bio, Inc. (NYSE: ANVS), a clinical-stage drug platform company developing novel therapies for neurodegenerative diseases, today announced the publication of new data from an earlier study supporting buntanetap as a translational inhibitor of amyloid precursor protein (APP) in patients with early Alzheimer's Disease (AD). Buntanetap is an oral molecule that selectively binds to an iron-responsive element in the mRNA of APP and other neurotoxic proteins and inhibits their translation. Through this mechanism, buntanetap was shown to decrease the production of amyloid beta (Aß), a key hallmark in AD. This study, which was finished in 2021, aimed to assess pharmacodynamic effects of buntanetap on the translation of APP mRNA by employing Stable Isotope Labeling Kinetics (SILK). SILK measures the translation, steady state, and degradation of a protein in the cerebrospinal fluid (CSF) and is able to detect subtle protein changes, whi
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News
- UPDATE 1-Annovis' Alzheimer's treatment helps improve cognition in trial [Yahoo! Finance]Yahoo! Finance
- Annovis Bio Announces Statistically Significant Phase II/III Data in Patients With Early Alzheimer's Disease [Yahoo! Finance]Yahoo! Finance
- Annovis Bio Announces Statistically Significant Phase II/III Data in Patients With Early Alzheimer’s DiseaseGlobeNewswire
- Annovis Bio, Inc. (NYSE: ANVS) had its "buy" rating re-affirmed by analysts at HC Wainwright. They now have a $30.00 price target on the stock.MarketBeat
- Annovis Bio Provides Corporate Updates and Reports Fourth Quarter and Full Year 2023 Financial Results [Yahoo! Finance]Yahoo! Finance
ANVS
Earnings
- 8/14/23 - Beat
ANVS
Sec Filings
- 4/29/24 - Form ARS
- 4/29/24 - Form DEFA14A
- 4/29/24 - Form DEF
- ANVS's page on the SEC website