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Stock impact report

Annovis Awarded $1.7 Million NIH Grant for ANVS401 Chronic Toxicology Studies

Annovis Bio, Inc. (ANVS) 
Company Research Source: GlobeNewswire
BERWYN, Pa., Feb. 27, 2020 (GLOBE NEWSWIRE) -- Annovis Bio Inc. (NYSE American: ANVS), a clinical-stage drug platform company addressing Alzheimer’s (AD) , Parkinson’s (PD) and other neurodegenerative diseases, was awarded a $1.7 million grant from the National Institutes of Health (NIH) for the Company’s long-term toxicology studies in rats and in dogs of its lead therapeutic compound ANVS401.  Annovis began the animal toxicology studies in the fourth quarter of 2019 and expects to complete the studies in the third quarter of 2020. Annovis previously conducted one-month safety studies in mice, rats and dogs, and conducted two human safety studies in 120 healthy volunteers.  In an interim analysis of an ongoing Phase 2a clinical trial in AD patients, the Data Safety Monitoring Board recommended the trial continue without modification.  In these one-month studies, ANVS401 was shown to be well tolerated.  Chronic toxicology studies are required to allow Annovis to test ANVS401 in hum Show less Read more
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