Apellis Reports Analysis from Phase 1b Geographic Atrophy Study
Apellis Pharmaceuticals, Inc. (APLS)
Company Research
Source: GlobeNewswire
No cases of inflammation observed after 12 months with Phase 3 formulation of pegcetacoplan in patients with advanced geographic atrophy (GA)Decrease in mean lesion growth in nine patients with bilateral GA consistent with Phase 2 FILLY studyPhase 3 DERBY and OAKS studies expected to fully enroll in the first half of 2020 WALTHAM, Mass., April 28, 2020 (GLOBE NEWSWIRE) -- Apellis Pharmaceuticals, Inc. (Nasdaq: APLS), a global biopharmaceutical company pioneering targeted C3 therapies, today announced early data from the Phase 1b APL2-103 study of pegcetacoplan (APL-2) in patients with advanced geographic atrophy (GA) and low vision. The study, which enrolled 12 patients, was initiated to assess the safety of the Phase 3 formulation of pegcetacoplan (15mg/0.1mL). Patients were dosed with pegcetacoplan in one eye using the fellow eye as untreated control. The analysis of APL2-103 has shown that the Phase 3 formulation was well tolerated over 12 months of treatment. Of the 12 patients
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