Aprea Therapeutics Announces Early Clinical Proof-Of-Concept in the Ongoing ACESOT-1051 Dose-Escalation Trial Evaluating WEE1 Inhibitor APR-1051, Including Partial Response Observed on Fir...
Aprea Therapeutics, Inc. (APRE)
Company Research
Source: GlobeNewswire
Approximately 50% reduction in target lesion and greater than 90% decrease in CA-125 observed in endometrial cancer patientThe unconfirmed partial response (uPR) that was observed in the first scan has been achieved at the 150 mg dose, with 220 mg cohort currently enrolling in the ACESOT-1051Potential dose-response trend observed with increasing single-agent activity across the 70 mg, 100 mg, and 150 mg cohortsData provide early clinical proof-of-concept for single-agent APR-1051 in patients with advanced solid tumors DOYLESTOWN, Pa., Jan. 29, 2026 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (Nasdaq: APRE) (“Aprea” or the “Company”), a clinical-stage biopharmaceutical company developing innovative therapies that exploit cancer-specific vulnerabilities while minimizing damage to healthy cells, today announced the first unconfirmed partial response (uPR) observed in a patient enrolled in its ongoing Phase 1 ACESOT-1051 dose-escalation study (A Multi-Center Evaluation of WEE1 Inhibit
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News
- Aprea Therapeutics (NASDAQ:APRE) had its "buy" rating reaffirmed by analysts at HC Wainwright. They now have a $4.00 price target on the stock, down previously from $5.00.MarketBeat
- Aprea Therapeutics Announces $5.6 Million Private Placement Priced At-The-Market Under Nasdaq RulesGlobeNewswire
- Aprea Therapeutics (NASDAQ:APRE) had its "sell (e+)" rating reaffirmed by analysts at <a style="font-weight:bold" href="https://weissratings.com/">Weiss Ratings</a>.MarketBeat
- Aprea Therapeutics (NASDAQ:APRE) was downgraded by analysts at Zacks Research from a "hold" rating to a "strong sell" rating.MarketBeat
- Aprea Therapeutics (NASDAQ:APRE) had its price target lowered by analysts at HC Wainwright from $20.00 to $5.00. They now have a "buy" rating on the stock.MarketBeat
APRE
Analyst Actions
- 1/29/26 - HC Wainwright
APRE
Sec Filings
- 2/2/26 - Form 4
- 2/2/26 - Form 4
- 1/29/26 - Form 8-K
- APRE's page on the SEC website