Aptose Presents New Preclinical Data on CG-806 PAN-FLT3/PAN-BTK Inhibitor at ASH 60th Annual Meeting
Aptose Biosciences, Inc. - Common Shares (APTO)
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Source: GlobeNewswire
SAN DIEGO and TORONTO, Dec. 03, 2018 (GLOBE NEWSWIRE) -- Aptose Biosciences Inc. (NASDAQ: APTO, TSX: APS) today announced the presentation of preclinical data from research led by The University of Texas MD Anderson Cancer Center exploring the mechanism by which CG-806, a highly potent pan-FLT3/pan-BTK inhibitor, overcomes the emergence of resistance common to other FLT3 inhibitors (FLT3i). The data were highlighted in a poster presentation on Sunday, December 2, 2018 at the American Society of Hematology (ASH) 60th Annual Meeting & Exposition, being held December 1-4 in San Diego, CA. Separately, Aptose and Oregon Health & Science University researchers also presented new data on CG-806 at ASH (see press release here). The poster Concomitant Targeting of FLT3 and BTK with CG-806 overcomes FLT3-Inhibitor Resistance Through Inhibition of Autophagy discusses the importance of FLT-3 targeted therapy for acute myeloid leukemia (AML), during which clinical benefit is often transient t
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