Aptinyx Presents Data Demonstrating Positive Activity of NYX-458 on Cognitive Performance and Biomarkers in a Preclinical Model of Head Injury
Aptinyx Inc. (APTX)
Last aptinyx inc. earnings: 3/30 04:01 pm
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Source: GlobeNewswire
EVANSTON, Ill., Aug. 21, 2019 (GLOBE NEWSWIRE) -- Aptinyx Inc. (Nasdaq: APTX), a clinical-stage biopharmaceutical company developing transformative therapies for the treatment of brain and nervous system disorders, today announced the presentation of preclinical data on its novel NMDA receptor modulator, NYX-458. The product candidate demonstrated positive recovery of performance on affective and spatial learning tasks that was impaired in a preclinical model of repeat closed head injury. In biomarker readings, NYX-458 also restored neuroendocrine function following disruption due to repeat closed head injury. These data will be exhibited in a poster presentation today at the 2019 Military Health System Research Symposium (MHSRS) in Kissimmee, Florida. “Traumatic brain injury often results in cognitive impairment and mood disturbances that have a significant impact on a person’s daily living and, unfortunately, there are very few treatment options available today to address these l
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