Aptevo Debuts First Trispecific Antibody Candidate, APVO451, with Preclinical Data Demonstrating Immune Activation in Hard-to-Treat Solid Tumors [Yahoo! Finance]
Aptevo Therapeutics Inc. (APVO)
Last aptevo therapeutics inc. earnings: 8/9 09:00 am
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Source: Yahoo! Finance
SEATTLE, WASHINGTON / ACCESS Newswire / November 10, 2025 / Aptevo Therapeutics ("Aptevo" or the "Company") (Nasdaq:APVO), a clinical-stage biotechnology company advancing differentiated immunotherapies, announced the first presentation of preclinical data for its new trispecific antibody, APVO451 , at the Society for Immunotherapy of Cancer (SITC) Annual Meeting on Saturday, November 8, 2025. The poster was presented by Michelle H. Nelson, PhD, Director of Immunobiology and Hieu Nguyen, BS, Senior Scientist, both of Aptevo. APVO451 is designed to solve a central challenge in the treatment of certain solid tumor types {such as urothelial, breast and pancreatic cancers}: The tumor microenvironment often shuts down the immune system's ability to fight cancer. The new molecule leverages Aptevo's proprietary use of the CRIS-7-derived CD3 binding domain-the same binding domain used in the Company's lead clinical drug, mipletamig, which has shown strong clinical activity with limited saf
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News
- Aptevo Therapeutics (NASDAQ:APVO) had its "sell (e)" rating reaffirmed by analysts at <a style="font-weight:bold" href="https://weissratings.com/">Weiss Ratings</a>.MarketBeat
- Aptevo Therapeutics (NASDAQ:APVO) had its "sell (e)" rating reaffirmed by analysts at <a style="font-weight:bold" href="https://weissratings.com/">Weiss Ratings</a>.MarketBeat
- Aptevo Presenting Scientific and Clinical Updates at SITC and ASH, also Participating in Leading Financial and Industry Conferences in the Fourth Quarter [Yahoo! Finance]Yahoo! Finance
- Aptevo Therapeutics (NASDAQ:APVO) had its "sell (e)" rating reaffirmed by analysts at <a style="font-weight:bold" href="https://weissratings.com/">Weiss Ratings</a>.MarketBeat
- Aptevo Therapeutics (NASDAQ:APVO) was upgraded by analysts at Zacks Research to a "hold" rating.MarketBeat
APVO
Sec Filings
- 11/26/25 - Form EFFECT
- 11/25/25 - Form 424B4
- 11/12/25 - Form 4
- APVO's page on the SEC website