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0.000651465798045589 0.00130293159609118 0.000651465798045589 0.000651465798045589 0.000651465798045589 0.00195439739413677 -0.00716612377850159 -0.00260586319218247
Stock impact report

JNJ Seeks FDA Approval for Oral Psoriasis Drug Icotrokinra [Yahoo! Finance]

Arvinas, Inc. (ARVN) 
Last arvinas, inc. earnings: 11/4 05:00 pm Check Earnings Report
Company Research Source: Yahoo! Finance
peptide, icotrokinra, for treating moderate-to-severe plaque psoriasis (PsO) in adults and pediatric patients aged 12 years and above. The NDA was based on data from four phase III studies, ICONIC-LEADa, ICONIC-TOTALb and ICONIC-ADVANCE 1 & ICONIC-ADVANCE 2 – all part of the ICONIC clinical development program evaluating icotrokinra, a IL-23 inhibitor across PsO and psoriatic arthritis indications. Across the four pivotal studies, treatment with icotrokinra achieved all primary and co-primary endpoints by showing significant skin clearance and a favorable safety profile with once-daily oral dosing in adults and adolescents with moderate-to-severe plaque PsO. Previously, data from the ICONIC-ADVANCE 1 and ICONIC-ADVANCE 2 studies, which evaluated icotrokinra against Bristol Myers ' BMY psoriasis drug, Sotyktu (deucravacitinib), also met the co-primary endpoints. The studies demonstrated the icotrokinra's superiority over Bristol Myers' Sotyktu. Shares of J&J have rallied 13.7% Show less Read more
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