Arrowhead Pharmaceuticals Files for Regulatory Clearance to Begin Phase 1/2a Study of ARO-ENaC for Treatment of Cystic Fibrosis
Arrowhead Pharmaceuticals, Inc. (ARWR)
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Source: Business Wire
PASADENA, Calif.--(BUSINESS WIRE)--Arrowhead Pharmaceuticals Inc. (NASDAQ: ARWR) today announced that it has filed an application for clearance to begin a Phase 1/2a clinical trial of ARO-ENaC, the company’s investigational RNA interference (RNAi) therapeutic being developed as a treatment for patients with cystic fibrosis (CF), which is a rare disease caused by genetic mutations that lead to progressive deterioration in lung function due to poor clearance of mucus and associated recurrent infections. ARO-ENaC utilizes Arrowhead’s proprietary Targeted RNAi Molecule (TRiM™) platform and is the company’s first inhaled RNAi candidate to target pulmonary epithelium.Chris Anzalone, Ph.D., president and chief executive officer of Arrowhead, said: “ARO-ENaC is Arrowhead’s second investigational RNAi therapeutic utilizing the TRiM™ platform to target tissues outside of the liver and the first to target a disease of the lungs. This CTA filing is the culmination of years of work by Arrowhea
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Sec Filings
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- 2/5/26 - Form 8-K
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