Arrowhead Pharmaceuticals Initiates Phase 1/2a Study of ARO-DM1 for Treatment of Type 1 Myotonic Dystrophy [Yahoo! Finance]
Arrowhead Pharmaceuticals, Inc. (ARWR)
Last arrowhead pharmaceuticals, inc. earnings: 2/5 04:00 pm
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Source: Yahoo! Finance
PASADENA, Calif., March 08, 2024 BUSINESS WIRE )--Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) announced today that it has dosed the first subjects in a Phase 1/2a double-blinded, placebo-controlled, dose-escalating study ( NCT06138743 ) to evaluate single and multiple ascending doses of ARO-DM1, the company's investigational RNA interference (RNAi) therapeutic, in up to 48 subjects with type 1 myotonic dystrophy (DM1). DM1 is the most common adult-onset muscular dystrophy. Patients with DM1 have muscle weakness and wasting, myotonia, cataracts, and often develop cardiac conduction abnormalities. Additionally, patients may become physically disabled and have a shortened life span. There is currently no approved disease-modifying therapy for DM1. Treatments have focused on symptomatic management, including physical therapy, exercise, ankle-foot orthoses, and assistive devices, such as wheelchairs. ARO-DM1 is designed to reduce expression of the dystrophia myotonica protein kinas
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News
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ARWR
Earnings
- 8/7/23 - Miss
ARWR
Sec Filings
- 4/10/24 - Form SC
- 4/3/24 - Form 4
- 4/1/24 - Form 144
- ARWR's page on the SEC website