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Stock impact report

aTyr Pharma Spotlights Efzofitimod Phase 3 Learnings, Eyes Mid-April FDA Type C Meeting [Yahoo! Finance]

aTyr Pharma, Inc. (ATYR) 
Company Research Source: Yahoo! Finance
placebo steroid withdrawal was higher than expected, but the 5 mg/kg dose showed statistically significant quality-of-life improvements (KSQ lung), a positive steroid-free+KSQ composite with dose response, preserved FVC versus placebo, and a favorable safety profile. aTyr has an FDA Type C meeting in mid-April to review EFZO-FIT; management says a filing would be “very challenging” after the primary miss and is preparing for the possibility the FDA will request another study, with any future trial likely to emphasize quality-of-life and pulmonary function endpoints by patient phenotype. The company's platform leverages tRNA synthetase fragments to modulate innate immunity in inflammatory ILDs, is advancing ATYR0101 as a potential anti-fibrotic and completing the Phase 2 EFZO-CONNECT scleroderma-ILD study, and reported roughly $80 million in cash at year-end. Interested in aTyr Pharma, Inc.? Here are five stocks we like better. aTyr Pharma (NASDAQ:ATYR) CEO Sanjay Shukla outlin Show less Read more
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