Autolus Therapeutics announces publication in Nature Communications
Autolus Therapeutics plc - American Depositary Shares (AUTL)
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Source: GlobeNewswire
LONDON, Feb. 22, 2024 (GLOBE NEWSWIRE) -- Autolus Therapeutics plc (Nasdaq: AUTL), a clinical-stage biopharmaceutical company developing next-generation programmed T cell therapies, today announces a publication in Nature Communications entitled: ‘Structure-Guided Engineering of Immunotherapies Targeting TRBC1 and TRBC2 in T Cell Malignancies.’1 In contrast to B cell lymphomas, T cell lymphomas have not benefited from immunotherapies such as therapeutic antibodies or CAR T cell therapies. This is because suitable surface target antigens are lacking. Immunotherapies for B cell lymphomas target pan B cell antigens, however an equivalent strategy targeting pan T cell antigens would lead to unacceptable immunosuppression. Nearly all T cell lymphomas express the aß T-cell receptor (TCRaß). There are two types of TCRaß - TRBC1 and TRBC2. While normal T cells are a mixture of approximately 40% TRBC1 and 60% TRBC2, T cell lymphomas are clonal so entirely express either TRBC1 or TRBC2
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- CAR T-Cell Therapy for Acute Lymphoblastic Leukemia Market to Register Stunning Growth by 2032, Predicts DelveInsight | Key Companies - AUTOLUS THERAPEUTICS, CELLECTIS, WUGEN, SERVIER, ALLOGENE, PRECISION BIOSCIENCESPR Newswire
- Autolus Therapeutics plc (NASDAQ: AUTL) had its "buy" rating re-affirmed by analysts at Needham & Company LLC. They now have a $9.00 price target on the stock.MarketBeat
- Autolus Therapeutics Reports First Quarter 2024 Financial Results and Business Updates [Yahoo! Finance]Yahoo! Finance
AUTL
Earnings
- 5/17/24 - Miss
AUTL
Sec Filings
- 5/21/24 - Form SC
- 5/17/24 - Form 10-Q
- 5/17/24 - Form 8-K
- AUTL's page on the SEC website