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Atea Pharmaceuticals Presents Preclinical Results Supporting First-in-Class Potential of AT-587 for Treatment of Hepatitis E Virus at CROI 2026

Atea Pharmaceuticals, Inc. - common stock (AVIR) 
Company Research Source: GlobeNewswire
Results Demonstrate AT-587 To Be Highly Potent In Vitro Against Hepatitis E Virus  Initiation of Phase 1 Clinical Program Anticipated Mid-2026 BOSTON, Feb. 24, 2026 (GLOBE NEWSWIRE) -- Atea Pharmaceuticals, Inc. (Nasdaq: AVIR) (Atea or Company), a late-stage clinical biopharmaceutical company engaged in the discovery and development of oral antiviral therapeutics for serious viral diseases, today announced in vitro results showing that two proprietary oral nucleotide analogs, AT-587 and AT-2490, exhibit promising antiviral profiles as potential first-in-class inhibitors for the treatment of Hepatitis E virus (HEV) infection, a positive-sense, single-stranded RNA virus that primarily infects liver cells. These results were presented at the Conference on Retroviruses and Opportunistic Infections (CROI), taking place February 22-25 in Denver, Colorado. In vitro studies demonstrated that AT-587 and AT-2490 were potent inhibitors of HEV replication. AT-587 and AT-2490 were 30-150-fold Show less Read more
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