Tectonic Therapeutic Initiates Phase 1B Study for TX45 in Group 2 Pulmonary Hypertension in Patients with Preserved Ejection Fraction Heart Failure [Yahoo! Finance]
AVROBIO, Inc. (AVRO)
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Source: Yahoo! Finance
TX45 clinical program advancing on track based on promising initial Phase 1A data; confirmatory Phase 1A data expected mid-2024 and topline Phase 1B data expected in 2025 WATERTOWN, Mass., March 26, 2024 BUSINESS WIRE )--Tectonic Therapeutic, Inc. ("Tectonic"), a privately-held biotechnology company developing GPCR (G-protein coupled receptor)-targeted therapeutic proteins, co-founded by Timothy A. Springer and Andrew C. Kruse of Harvard Medical School, today announced the initiation of enrollment in the Phase 1B study for TX45, an investigational long-acting relaxin-Fc fusion molecule. The study will evaluate the safety and hemodynamic effects of single-dose TX45 in patients with Group 2 Pulmonary Hypertension secondary to Heart Failure with preserved Ejection Fraction (Group 2 PH with HFpEF). Group 2 PH with HFpEF impacts over 600,000 patients in the US and is associated with significant morbidity and mortality. Importantly, there are no approved therapies for this condition. "
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- Tectonic Therapeutic Initiates Phase 1B Study for TX45 in Group 2 Pulmonary Hypertension in Patients with Preserved Ejection Fraction Heart FailureBusiness Wire
- SHAREHOLDER UPDATE: Halper Sadeh LLC Investigates CHRD, KAMN, CTLT, AVROAccesswire
- Kuehn Law Encourages CHRD, AVRO, KAMN, and CTLT Investors to Contact Law FirmPR Newswire
- Tectonic Therapeutic Announces Participation at Investor Conferences in MarchBusiness Wire
- SHAREHOLDER UPDATE: Halper Sadeh LLC Investigates CALB, AVRO, GLT, FREEPR Newswire
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- 3/26/24 - Form S-4/A
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