AstraZeneca's Fasenra: Approval for asthma may initiate COPD approval [Yahoo! Finance]
AstraZeneca PLC - American Depositary Shares (AZN)
Last astrazeneca plc - american depositary shares earnings: 2/5 04:00 pm
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Source: Yahoo! Finance
Fasenra is a monoclonal antibody that inhibits the alpha subunit of the interleukin-5 receptor found on eosinophils and attracts natural killer cells to induce the near-complete depletion of eosinophils via programmed cell death. It was first approved in 2017 in the US as an add-on maintenance therapy for the treatment of severe eosinophilic asthma in patients aged 12 years and older and is currently undergoing a Phase III clinical trial for chronic obstructive pulmonary disease (COPD). According to leading data and analytics company GlobalData 's Sales and Forecast database, total sales for Fasenra are set to reach $2.0bn globally by 2029. COPD is a heterogeneous, progressive lung disease characterised by chronic symptoms, including dyspnea, cough, sputum production, and/or exacerbations (GOLD, 2022). Therapies for COPD have been in development for decades to reduce exacerbations and manage the symptom load of the disease, with biologics dominating the late-stage COPD pipeli
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