ENHERTU® Demonstrated Statistically Significant and Clinically Meaningful Improvement in Progression-Free Survival in HR Positive, HER2 Low Metastatic Breast Cancer Following One or More L...
AstraZeneca PLC - American Depositary Shares (AZN)
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Source: Yahoo!
Plans for global regulatory submissions are underway TOKYO & BASKING RIDGE, N.J., April 29, 2024 BUSINESS WIRE )--Positive topline results from the DESTINY-Breast06 phase 3 trial showed that ENHERTU ® (trastuzumab deruxtecan) demonstrated a statistically significant and clinically meaningful improvement in progression-free survival (PFS) compared to standard of care chemotherapy in the primary trial population of patients with HR positive, HER2 low (IHC 1+ or IHC 2+/ISH-) metastatic breast cancer following one or more lines of endocrine therapy. A statistically significant and clinically meaningful improvement in PFS also was observed in the overall trial population (patients with HER2 low and HER2 ultralow [defined as IHC 0 with membrane staining; IHC 0 Overall survival (OS) data were not mature at the time of the analysis. However, ENHERTU showed an early trend towards an OS improvement versus standard of care chemotherapy in patients with HER2 low metastatic breast cancer a
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AZN
Sec Filings
- 5/7/24 - Form 6-K
- 5/2/24 - Form 6-K
- 5/1/24 - Form 6-K
- AZN's page on the SEC website