AstraZeneca reports positive interim data from mantle cell lymphoma trial [Yahoo! Finance]
AstraZeneca PLC - American Depositary Shares (AZN)
Last astrazeneca plc - american depositary shares earnings: 2/5 04:00 pm
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Source: Yahoo! Finance
Calquence (acalabrutinib) in combination with standard chemoimmunotherapy for treating mantle cell lymphoma (MCL). The double-blind, randomised, placebo-controlled, multicentre trial involved adult patients aged 65 years and above with priorly untreated MCL. It is designed to assess the safety and efficacy of Calquence plus standard-of-care chemoimmunotherapy comprising bendamustine and rituximab, compared to standard of care chemoimmunotherapy alone. Progression-free survival (PFS) is the trial's primary endpoint with key secondary endpoints including overall survival (OS), overall response rate (ORR), duration of response (DoR), and time to response (TTR). The trial is being carried out in 27 countries across North and South America, Europe, Asia, and Oceania. According to the findings, a statistically significant and clinically meaningful improvement in PFS was observed in patients treated with the Calquence regimen compared to the standard of care alone. A trend toward
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AZN
Sec Filings
- 5/21/24 - Form 6-K
- 5/20/24 - Form 6-K
- 5/16/24 - Form 6-K
- AZN's page on the SEC website