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-0.00047561168947828 -0.00184960101463824 -0.00121545209533367 -0.000686994662579905 0.00248374993394297 0.00482111715901293 0.00539026581408873 0.00829519632193633
Stock impact report

Tozorakimab met primary endpoint in both OBERON and TITANIA Phase III trials in patients with COPD

AstraZeneca PLC Ordinary Shares (AZN) 
Last astrazeneca plc ordinary shares earnings: 2/5 04:00 pm Check Earnings Report
US:NYSE Investor Relations: astrazeneca.com/investor-relations.html
Company Research Source: Business Wire
First-ever IL-33-targeting biologic to demonstrate statistically significant and highly clinically meaningful reductions in COPD exacerbations in two replicate Phase III clinical trials WILMINGTON, Del.--(BUSINESS WIRE)--Positive high-level results from the Phase III OBERON and TITANIA trials in patients with chronic obstructive pulmonary disease (COPD) showed that tozorakimab reduced the annualized rate of moderate-to-severe COPD exacerbations compared with placebo, in the primary population of former smokers, and in the overall population, which included former and current smokers, and patients across all blood eosinophil* counts and all stages of lung function severity. Tozorakimab was generally well tolerated with a favorable safety profile.Tozorakimab is a potential first-in-class monoclonal antibody targeting interleukin-33 (IL-33), that uniquely inhibits the signaling of the reduced and oxidized forms of IL-33, offering the potential to both reduce inflammation and disrupt t Show less Read more
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