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Bicara Therapeutics Talks Ficerasfusp Alfa Data, Pivotal Trial Timeline and $172M Raise at Conference [Yahoo! Finance]

Bicara Therapeutics Inc. (BCAX) 
Company Research Source: Yahoo! Finance
Phase III for recurrent/metastatic HPV-negative head and neck cancer, using a 1,500 mg pivotal dose with ORR as a potential accelerated approval endpoint and top-line data expected in mid-2027 (trial ~600–650 patients; ORR analysis triggered at ~350 patients with blinded OS follow-up). Clinical data reported deep, durable activity: the 1,500 mg dose showed a 21% complete response rate and a 55% confirmed response rate with a 21.7-month median duration of response in HPV-negative patients, which Bicara contrasted favorably versus pembrolizumab monotherapy. Bicara's TGF-beta “trap” uses a TGFBR2-based design to preferentially target TGF-beta1/3 and mitigate prior TGF-beta toxicities, and the company recently raised $172 million to support U.S. commercial buildout, parallel randomized studies, and further indication expansion. Interested in Bicara Therapeutics Inc.? Here are five stocks we like better. Bicara Therapeutics (NASDAQ:BCAX) is developing tumor-targeting bifunctional a Show less Read more
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