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Beam Therapeutics Announces Clearance of Clinical Trial Authorisation Application for BEAM-302 for the Treatment of Alpha-1 Antitrypsin Deficiency (AATD) [Yahoo! Finance]

Beam Therapeutics Inc. (BEAM) 
Company Research Source: Yahoo! Finance
CAMBRIDGE, Mass., March 26, 2024 (GLOBE NEWSWIRE) -- Beam Therapeutics Inc. (Nasdaq: BEAM), a biotechnology company developing precision genetic medicines through base editing, today announced the clearance of its clinical trial authorisation (CTA) application by the United Kingdom (UK) Medicines and Healthcare Products Regulatory Agency for BEAM-302, an in vivo base editor, as a potential treatment for patients with alpha-1 antitrypsin deficiency (AATD). “The clearance of our first CTA is an important step in the advancement of our global Phase 1/2 study of BEAM-302, a potentially best-in-class, liver-targeting in vivo base editor designed to correct the PiZ mutation, which is the most common gene variant associated with severe AATD,” said Giuseppe Ciaramella, Ph.D., president of Beam. “AATD is an inherited genetic condition that can cause serious lung and liver disease, which can lead to significant debility and reduced life expectancy for patients. Preclinical data demonstrated Show less Read more
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