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Stock impact report

Beam Therapeutics: Base Editing Leader With Major Catalyst Next Year [Seeking Alpha]

Beam Therapeutics Inc. (BEAM) 
Company Research Source: Seeking Alpha
asbeI covered Beam Therapeutics (NASDAQ:BEAMCo-foundedby David Liu, the Broad Institute and Harvard biochemist who also founded Editas, Beam is the leading developer of genetic therapies using base editing. Base editing is the simplest form of gene editing that changes a single DNA letter. It also has exclusive rights to prime editing technology, which can insert or delete longer DNAs.Interestingly, while prime editing is the next generation technology compared, in some respects, to even CRISPR/Cas9, Beam's current pipeline is entirely focused on base editing. It has only one clinical program, BEAM-101 for Sickle Cell Disease or SCD, and this program is all base editing. Its IND was cleared last year.Beam also licensed its base editing technology to Verve Therapeutics (VERVarticleBEAM-101 has broadly successful data in animal studies. The technology edits a certain point mutation, inducing it to cause these cells to exhibit a hereditary trait seen in certain individuals where they per Show less Read more
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