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Beam Therapeutics Inc. (BEAM) Reports Updated Data From BEACON Phase 1/2 trial Of Ristoglogene [Yahoo! Finance]

Beam Therapeutics Inc. (BEAM) 
Company Research Source: Yahoo! Finance
TheFly reported on December 2, 2025, that Beam Therapeutics Inc. (NASDAQ:BEAM) has released revised safety and effectiveness information from its BEACON Phase 1/2 clinical trial evaluating ristoglogene autogetemcel (previously BEAM-101). It is an investigational genetically engineered ex vivo base editing cell therapy for sickle cell disease patients suffering from severe vaso-occlusive crises. The information was shown during the 67th Annual Meeting and Exposition of the American Society of Hematology in Orlando. A total of 31 adults and adolescents were treated with risto-cel and were included in the updated results. The company reported a decline of hemoglobin S to less than 40%, a remission of anemia that lasted up to 20 months, and a mean fetal hemoglobin induction of more than 60%. A median of one cell collection cycle was needed for each patient. After treatment, rapid neutrophil and platelet engraftment were seen. According to the firm, busulfan conditioning, autologous hem Show less Read more
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