Hemispherian Initiates Phase 1/2a Clinical Trial of GLIX1 in Glioblastoma [Yahoo! Finance]
BioLineRx Ltd. - American Depositary Shares (BLRX)
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Source: Yahoo! Finance
Study led by world-leading glioblastoma investigators, including Dr. Roger Stupp OSLO, Norway, April 08, 2026 BUSINESS WIRE )--Hemispherian AS, a clinical-stage oncology company developing novel small molecule therapeutics, today announced the initiation of a first-in-human Phase 1/2a clinical trial of GLIX1 in patients with recurrent and progressive glioblastoma (GBM) and other high-grade gliomas (NCT07464925). The study is being conducted in collaboration with BioLineRx Ltd. (NASDAQ/TASE: BLRX). GLIX1 is an orally available, first-in-class small molecule designed to activate TET2 and drive tumor-selective DNA damage. By restoring TET2 activity, GLIX1 induces DNA damage selectively in cancer cells, representing a differentiated approach to targeting the DNA damage response with potential applicability across a broad range of tumors. Glioblastoma was selected as the initial indication due to its highly suppressed TET2 activity and significant unmet medical need. Despite existin
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News
- Hemispherian Initiates Phase 1/2a Clinical Trial of GLIX1 in GlioblastomaBusiness Wire
- BioLineRx Announces Initiation of Phase 1/2a Study of GLIX1 for the Treatment of Glioblastoma (GBM)PR Newswire
- BioLine Rx Ltd (BLRX) Full Year 2025 Earnings Call Highlights: Navigating Challenges and ... [Yahoo! Finance]Yahoo! Finance
- BioLineRx Ltd. (BLRX) Q4 2025 Earnings Call Transcript [Seeking Alpha]Seeking Alpha
- BioLineRx GAAP EPS of $0.00 beats by $0.68, revenue of $1.18M misses by $0.3M [Seeking Alpha]Seeking Alpha
BLRX
Sec Filings
- 4/10/26 - Form 3
- 3/31/26 - Form 3
- 3/31/26 - Form 3
- BLRX's page on the SEC website