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-0.00121359223300971 0.000693481276005656 -0.000693481276005533 -0.00277392510402213 -0.00277392510402213 -0.00173370319001377 -0.00312066574202496 -0.00112690707350898
Stock impact report

BioMarin stops mid-stage trials of bone disorder treatment [Yahoo! Finance]

BioMarin Pharmaceutical Inc. (BMRN) 
Last biomarin pharmaceutical inc. earnings: 4/29 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: investors.biomarin.com
Company Research Source: Yahoo! Finance
patients' hip joint ?slipping out of place, the drugmaker said on Monday, sending ?its shares down 4%. * BioMarin was testing its drug Voxzogo in patients withTurner Syndrome, SHOX-deficiency and Aggrecan (ACAN)-deficiency,which are distinct genetic conditions that causes severe shortstature and in ?some cases abnormal ?bone development. * Turner syndrome occurs in females missing part or all ofan X chromosome, ?SHOX deficiency results from a missing orfaulty growth-related gene, and ACAN deficiency is caused bymutations in a ?gene important ?for cartilage structure. * During ?the mid-stage trials, several ?patients facedslipped capital femoral epiphysis, where the ball of the hipjoint slips off the thigh bone at the area where the bone isstill growing. * BioMarin said it will continue testing the drug inpatients with Noonan ?syndrome where typical development stops ?invarious parts of the body, ?and in patients ?with a form ofunexplained short stature. * The ?U.S. Food and Drug Adm Show less Read more
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