Denovo Announces Issuance of U.S. Patent of Novel Genetic Biomarker ANK3 (DGM4™) for Liafensine (DB104) [Yahoo! Finance]
Bristol-Myers Squibb Company (BMY)
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Source: Yahoo! Finance
SAN DIEGO, April 29, 2026 (GLOBE NEWSWIRE) -- Denovo Biopharma, a pioneer in applying precision medicine in central nervous system (CNS) diseases, today announced that the U.S. Patent and Trademark Office issued U.S. patent number 12,612,261, titled “ Compositions and methods for assessing the efficacy of inhibitors of neurotransmitter transporters .” The patent is directed for the use of DGM4™, a novel genetic biomarker discovered through the company's AI and big data based Denovo Genomic Marker (DGM™) platform, for the company's DB104 (liafensine) program for treatment-resistant depression (TRD). “The patent issuance for the DGM4 biomarker represents a significant step in strengthening our DB104 intellectual property portfolio and reinforces our mission to redefine the treatment of TRD, a difficult-to-treat CNS disorder that impacts millions of patients globally,” said Wen Luo, PhD, Denovo's Chief Executive Officer. “Building on the success of our Phase 2b study and Fast Track De
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