Bristol-Myers Squibb Reports Positive Phase 3 SCOUT-HCM Results for Camzyos in Adolescent Patients [Yahoo! Finance]
Bristol-Myers Squibb Company (BMY)
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Source: Yahoo! Finance
topline results from its Phase 3 SCOUT-HCM clinical trial. This study evaluated Camzyos (mavacamten), which is a cardiac myosin inhibitor/CMI, in adolescent patients aged 12 to under 18 years suffering from symptomatic obstructive hypertrophic cardiomyopathy/oHCM. This rare genetic disease causes heart muscle thickening that obstructs blood flow, leading to significant fatigue and restricted physical activity in young patients. The SCOUT-HCM trial successfully met its primary endpoint by demonstrating a statistically significant reduction in the Valsalva left ventricular outflow tract/LVOT gradient at Week 28 compared to a placebo. This measurement indicates that the medication effectively reduced the physical obstruction in the heart. Furthermore, the trial reached statistical significance across multiple secondary endpoints. These results suggest that Camzyos could become the first CMI specifically approved for the adolescent population, who currently rely on limited medical manag
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BMY
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- 10/31/25 - Beat
BMY
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