Crescendo Biologics presents preclinical data on lead clinical candidate CB307 and unveils its first ‘2 in 1' immune cell engager CB699 at AACR 2024 [Yahoo! Finance]
BioNTech SE - American Depositary Shares (BNTX)
Company Research
Source: Yahoo! Finance
Preclinical data demonstrate strong rationale for ongoing Phase 1b POTENTIA trial investigating conditional CD137 (4-1BB) agonist CB307 as monotherapy and in combination with pembrolizumab in patients with prostate cancer Simultaneous publication in prestigious Clinical Cancer Research journal, including research generated through successful collaboration with The Institute of Cancer Research, London Crescendo also debuts CB699, a mesothelin-directed, CD137 and CD40 dual agonist demonstrating tumour-targeted activation of T, NK, and B lymphocytes Cambridge, UK, 10 April 2024 – Crescendo Biologics Ltd (Crescendo), a clinical stage immuno-oncology company developing novel, targeted immune cell enhancing therapeutics, has presented preclinical data at the 2024 American Association for Cancer Research (AACR) Annual Meeting on its two leading programmes: Clinical programme CB307 a ‘1st and only' in class CD137 (4-1BB) x PSMA bispecific for end-stage prostate cancer patients Firs
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