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Stock impact report

Project Optimus: helping or hindering cancer drug development? [Yahoo! Finance]

Blueprint Medicines Corporation (BPMC) 
Last blueprint medicines corporation earnings: 2/13 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: blueprintmedicines.com
Company Research Source: Yahoo! Finance
implementation efforts in a bid to drive innovation in drug development. Agency eyes have zeroed in on oncology, with the FDA Oncology Center of Excellence (OCE) introducing frameworks such as Project Optimus to reform the dose optimization and dose selection paradigm in oncology drug development. While the framework of Optimus is not new to drug development, it is relatively new to oncology. In non-deadly indications, researchers have been employing the framework for quite some time because the chances of patient survival are higher, making drug toxicity less acceptable in these indications compared to a high-morbidity indication such as cancer, says Dr. Fouad Namouni, President of Research & Development at Blueprint Medicines. The philosophy of oncology drug development—both academically and in pharma—is to save patient lives. However, development has historically prioritised drug efficacy and eliminating the tumour and cancer at the expense of increased treatment toxicities. Th Show less Read more
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