Melinta Therapeutics’ Topical Radezolid Well Tolerated in Phase 1 Study for Treatment of Acne
CEMPRA (CEMP)
US:NASDAQ Investor Relations:
ir.melinta.com/investor-relations
Company Research
Source: GlobeNewswire
NEW HAVEN, Conn., Oct. 10, 2017 (GLOBE NEWSWIRE) -- Melinta Therapeutics, a privately held commercial-stage company developing and commercializing novel antibiotics to treat serious bacterial infections, announced today that a Phase 1 clinical study of topical radezolid for the treatment of mild-to-moderate acne vulgaris has been successfully completed. Melinta and its partner enrolled 10 individuals with grade 3-to-4 acne vulgaris who applied topical radezolid twice daily for four weeks. Results demonstrated that radezolid was well tolerated with minimal systemic absorption. Acne is caused by the bacterium, Propionibacterium acnes, and is one of the most commonly treated skin disorders, affecting up to 50 million Americans. Resistance to antimicrobial treatments for acne has been shown to be as high as 66 percent. A separate in vitro study sponsored by Melinta against contemporary (2017) bacterial strains from acne patients that include isolates resistant to commonly used topical
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