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Stock impact report

Why Is Cullinan Therapeutics Stock Trading Higher On Wednesday? [Yahoo! Finance]

Cullinan Therapeutics, Inc. (CGEM) 
Company Research Source: Yahoo! Finance
The findings have implications for Cullinan Therapeutics Inc's (NASDAQ: CGEM ) CLN-978, a similar CD19xCD3 bispecific T-cell engager. Most recently, Cullinan Therapeutics, formerly Cullinan Oncology, announced its plans to expand into autoimmune diseases and intends to pursue the development of CLN-978 in autoimmune diseases, with systemic lupus erythematosus (SLE) as a first indication William Blair notes that the case report demonstrates that Blincyto effectively treated a patient with severe systemic sclerosis, leading to rapid B-cell depletion and symptom improvement without increasing infection risk or affecting antibody levels. This suggests the potential for using B-cell-depleting therapy in autoimmune diseases like systemic lupus erythematosus (SLE), offering easier administration than CAR-T therapy. CLN-978's development will initially target SLE, with Phase 1 submission planned for the third quarter. William Blair rates Cullinan shares Outperform based on the sign Show less Read more
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