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Stock impact report

Cognition Therapeutics Releases New Episode of “Conversations” Podcast: Protecting the Synapse from Amyloid Toxicity in Alzheimer's Disease [Yahoo! Finance]

Cognition Therapeutics, Inc. (CGTX) 
Company Research Source: Yahoo! Finance
developing drugs that treat neurodegenerative disorders, has released its eighth Conversations video podcast episode: “Protecting the Synapse from Amyloid Toxicity in Alzheimer's Disease.” This episode reviews how beta amyloid (Aß) oligomers cause synaptic dysfunction, which is correlated with cognitive decline. This conversation features a discussion of newly published research showing that Aß oligomers bind to synapses in brain tissue of Alzheimer's patients and how CT1812 acts to reverse their binding and reduce synaptotoxicity. Additionally, the panelists discuss using quantitative electroencephalography (EEG) as a real-time biomarker of synaptic function. In the Phase 2 ‘ SEQUEL' study of CT1812 in mild-to-moderate Alzheimer's disease, four weeks of treatment was associated with trends to improvement in synaptic function and brain connectivity. Finally, Dr. Hamby summarized results of proteomic analysis demonstrating the impact of CT1812 treatment on proteins and pathways alter Show less Read more
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