Celldex Announces Initial Positive Results from Phase 1 Trial of CDX-622 Demonstrating Favorable Safety and PK Profile and Sustained Mast Cell Inhibition
Celldex Therapeutics, Inc. (CLDX)
Last celldex therapeutics, inc. earnings: 11/12 08:01 am
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Source: GlobeNewswire
--Data from Phase 1 Study in healthy volunteers presented at CIA Biennial Symposium-- HAMPTON, N.J., Oct. 30, 2025 (GLOBE NEWSWIRE) -- Celldex (NASDAQ:CLDX) announced today positive data from the ongoing Phase 1 study of CDX-622, a novel bispecific antibody that targets two non-redundant, complementary pathways implicated in inflammation and fibrosis—mast cell depletion via stem cell factor (SCF) starvation and neutralization of the alarmin thymic stromal lymphopoietin (TSLP). CDX-622 was well tolerated, exhibited a good pharmacokinetic profile and induced rapid and sustained reductions in serum tryptase, indicative of mast cell inhibition and depletion. The data were presented by Diego Alvarado, PhD, Vice President of Research at Celldex, in an oral presentation at the CIA (Collegium Internationale Allergologicum) Biennial Symposium in Dubrovnik, Croatia. “Celldex continues to lead the field in therapeutic targeting of mast cells, presenting promising data today from the first st
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CLDX
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- 11/10/25 - Miss
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- 12/4/25 - Form 144
- 11/17/25 - Form 4
- 11/14/25 - Form SCHEDULE
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