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Stock impact report

Climb Bio Highlights Budoprutug and CLYM116 Milestones, Sets Up “Rich Data Year” in 2026 [Yahoo! Finance]

Climb Bio, Inc. (CLYM) 
Company Research Source: Yahoo! Finance
2026 and initial clinical readouts for PMN, ITP and SLE in H2 2026, while healthy-volunteer data for CLYM116 is expected around midyear. Budoprutug is a CD19 monoclonal being developed as a subcutaneous B-cell depleter targeting PMN, ITP and SLE; the program emphasizes biomarker and B-cell depletion readouts and is positioned as a broader/ repeatable alternative to CD20 therapies. CLYM116 is an APRIL-only “sweeper” antibody with pH-dependent binding and FcRn recycling that showed up to ~80% IgA reduction in NHPs; mid-2026 healthy-volunteer data will assess PK, IgA lowering and immunogenicity as the company targets IgA nephropathy. Interested in Climb Bio, Inc.? Here are five stocks we like better. Climb Bio (NASDAQ:CLYM) used a presentation at the Leerink Partners Global Healthcare Conference to outline its strategy around two immune-focused programs and to preview a series of data readouts expected in 2026. Chief Executive Officer Aoife Brennan and Chief Financial Officer Sus Show less Read more
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