Compass Therapeutics Presents Data Demonstrating Elimination of MHC Class I Negative Tumors in In Vivo Models at the 2024 American Association for Cancer Research (AACR) Annual Meeting [Ya...
Compass Therapeutics, Inc. (CMPX)
Company Research
Source: Yahoo! Finance
blockers, due to the loss of the fundamental recognition of the tumor by CD8+ T-Cells, which drive the adaptive immune attack on the tumor. Immune responses were generated toward the MHC-I negative tumors by combining CTX-009 with CTX-471. This combination was surprisingly synergistic. The proposed mechanism for this effect suggests the involvement of NK-cells, which can generate potent cell killing independent of MHC-I. By blocking DLL4 and VEGF, CTX-009 may increase the trafficking and penetration of NK Cells into the tumor microenvironment where CTX-471 may augment the activity of these cells. This activity against the tumor does not require MHC-I integrity. The combination of CTX-009 and CTX-471 has the potential to be an effective therapeutic regimen in patients who have previously progressed on checkpoint blockers, such as anti-PD-1 and anti-PD-L1 antibodies. BOSTON, April 09, 2024 (GLOBE NEWSWIRE) -- Compass Therapeutics, Inc. (Nasdaq: CMPX), a clinical-stage, oncology-
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News
- Compass Therapeutics Receives FDA Fast Track Designation for the Investigation of CTX-009 in Combination with Paclitaxel for the Treatment of Patients with Metastatic or Locally Advanced Biliary Tract Tumors That Have Been Previously Treated [Yahoo! FinanYahoo! Finan
- Compass Therapeutics Receives FDA Fast Track Designation for the Investigation of CTX-009 in Combination with Paclitaxel for the Treatment of Patients with Metastatic or Locally Advanced Biliary Tract Tumors That Have Been Previously TreatedGlobeNewswire
- Compass Therapeutics, Inc. (NASDAQ: CMPX) had its "buy" rating re-affirmed by analysts at HC Wainwright. They now have a $10.00 price target on the stock.MarketBeat
- Compass Therapeutics Announces First Patient Dosed in the Phase 1 Study of CTX-8371 in Patients with Solid Tumors [Yahoo! Finance]Yahoo! Finance
- Compass Therapeutics Announces First Patient Dosed in the Phase 1 Study of CTX-8371 in Patients with Solid TumorsGlobeNewswire
CMPX
Earnings
- 3/21/24 - Miss
CMPX
Sec Filings
- 4/29/24 - Form ARS
- 4/29/24 - Form DEFA14A
- 4/29/24 - Form DEF
- CMPX's page on the SEC website