Constellation Pharma down 1% on CPI-1205 data [Seeking Alpha]
Constellation Pharmaceuticals, Inc (CNST)
Last constellation pharmaceuticals, inc earnings: 3/10 04:12 pm
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Source: Seeking Alpha
Constellation Pharma down 1% on CPI-1205 data Thinly traded micro cap Constellation Pharmaceuticals ( CNST -1.4% results ProSTAR Clinical activity was observed in both arms, including at least a 50% drop in PSA levels. Specifically, 20% (n=2/10) patients in the CPI-1205 + abiraterone arm who were negative for a genetic variant called AR-V7 experienced at least an 80% reduction in PSA while 27% (n=3/11) in the CPI-1205 group (negative for AR-V7) did. The disease control rates (responders + stable cancer) in both groups were 50% (n=4/8) and 60% (n=3/5), respectively. The Phase 2 portion was launched in Q4 2018. Preliminary data should be available in H2. CPI-1205 inhibits an enzyme called enhancer of zeste homolog 2 (EZH2), associated with many types of cancer when overexpressed. Related tickers: ( JNJ -0.6% PFE +0.8% OTCPK:ALPMY +1.7%
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