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Stock impact report

Centessa Pharmaceuticals Announces Poster Presentation of New Preclinical Data Supporting Expansion of Orexin Receptor 2 (OX2R) Agonist Pipeline into Neuropsychiatric Indications at the 64...

Centessa Pharmaceuticals plc - American Depositary Shares (CNTA) 
Company Research Source: Yahoo! Finance
BOSTON and LONDON, Jan. 14, 2026 (GLOBE NEWSWIRE) -- Centessa Pharmaceuticals plc (Nasdaq: CNTA), a clinical-stage pharmaceutical company focused on developing transformational medicines, today announced the presentation of new preclinical data showing that OX2R activation with a highly potent and selective OX2R agonist reduced behavioral despair and enhanced wakefulness in an established animal model of major depressive disorder at the 64th Annual Meeting of the American College of Neuropsychopharmacology (ACNP). These results support OX2R activation as a potential mechanism of action for rapid-onset treatment to improve mood symptoms and alleviate hypersomnolence in neuropsychiatric indications. “As a leader in orexin science, we continue to explore orexin pharmacology within a suite of well validated translational non-clinical studies with the goal of unlocking the full potential of our multi-asset OX2R agonist pipeline for patients,” said Mario Alberto Accardi PhD, Chief Execut Show less Read more
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