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Centessa Pharmaceuticals Teases ORX750 Phase II Update, Registrational Study Start at Conference [Yahoo! Finance]

Centessa Pharmaceuticals plc - American Depositary Shares (CNTA) 
Company Research Source: Yahoo! Finance
and aims to start registrational studies for rare hypersomnias (NT2 and idiopathic hypersomnia) this quarter while outlining registrational design and regulatory strategy. November low-dose results showed clinically meaningful effects — 20-minute placebo-adjusted MWT improvement in NT1, 10-minute in NT2, normalization of ESS scores and statistically significant benefits in IH — with a favorable safety/tolerability profile and only mild, transient visual events reported. Centessa is escalating doses and testing once-daily and split-dosing to extend duration of action and patient flexibility, expanded the Phase II open-label extension to four weeks with no loss of effect, and is preparing regulatory engagement, commercial hiring, and follow-on orexin assets (ORX142, ORX489). Interested in Centessa Pharmaceuticals PLC Sponsored ADR? Here are five stocks we like better. Wake Up to This Biotech Stock That Still Has Big Potential Upside Centessa Pharmaceuticals (NASDAQ:CNTA) used Show less Read more
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