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Stock impact report

Charles River (CRL) Forges Collaboration With Ship of Theseus [Yahoo! Finance]

Charles River Laboratories International, Inc. (CRL) 
Last charles river laboratories international, inc. earnings: 2/11 07:00 am Check Earnings Report
US:NYSE Investor Relations: ir.criver.com
Company Research Source: Yahoo! Finance
manufacturing organization (“CDMO”) agreement with Ship of Theseus, a therapeutics company developing degradation-resistant homeobox (HOX) family biologics. Under the collaboration, the latter will leverage Charles River's premier expertise to manufacture GMP plasmid DNA to serve as the active drug substance for its lead candidate. The latest development is also expected to significantly boost the company's Manufacturing Solutions segment. Significance of the Collaboration Ship of Theseus is developing a proprietary suite of biologics based on the HOX family of transcription factors, which are responsible for driving the differentiation of tissue stem cells toward their respective lineages to repair and maintain the correct function of tissues and organs. Proprietary modifications may enable these regulators to be used as therapeutics. The partnership between Charles River and Ship of Theseus aims to support therapeutic development for a broad variety of target indications, su Show less Read more
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