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Stock impact report

Charles River Highlights Effectiveness of VCGs in Toxicology [Yahoo! Finance]

Charles River Laboratories International, Inc. (CRL) 
Last charles river laboratories international, inc. earnings: 2/11 07:00 am Check Earnings Report
US:NYSE Investor Relations: ir.criver.com
Company Research Source: Yahoo! Finance
WILMINGTON, Mass., April 21, 2026 BUSINESS WIRE )--Charles River Laboratories International, Inc. (NYSE: CRL) has shared the results of a retrospective analysis in Regulatory Toxicology and Pharmacology , showing that virtual control groups (VCGs) can preserve scientific integrity while reducing reliance on animal models. The review, which looked at 20 toxicology studies that replaced concurrent control groups (CCGs) with curated VCGs, and compared the outcomes across study-level decisions and detailed endpoints. There was 100 percent concordance in the No Observed Adverse Effect Level (NOAEL) across all studies, and although there was some minor endpoint-level variability between the CCG and VCG, the core study conclusions remained unchanged. Continued research with clients has been ongoing to enhance and refine models to address these variabilities. Charles River's VCG program is guided by the Alternative Methods Advancement Project™ (AMAP), an initiative focused on reducing the us Show less Read more
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