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Stock impact report

CVKD: Phase 2 HIT Results Show Encouraging Reduction in Thrombotic Events [Yahoo! Finance]

Cadrenal Therapeutics, Inc. (CVKD) 
Company Research Source: Yahoo! Finance
By David Bautz, PhD NASDAQ:CVKD READ THE FULL CVKD RESEARCH REPORT Business Update Encouraging Results from Phase 2 HIT Trial On February 24, 2026, Cadrenal Therapeutics, Inc. (NASDAQ:CVKD) announced encouraging results from the Phase 2 trial of CAD-1005 (formerly CAD-1005) in heparin-induced thrombocytopenia (HIT). The results showed a meaningful reduction in thrombotic events despite not meeting the study's primary endpoint of platelet count recovery. While platelet recovery did not differ between treatment groups, thrombotic events occurred in 50% of CAD-1005-treated patients compared with 75% in placebo-treated patients, which represents a 25% absolute reduction. Although the study was not powered for statistical significance, the signal is clinically compelling in a condition with a high morbidity and mortality, and no approved therapies specifically targeting the immune mechanism underlying HIT. The randomized, placebo controlled Phase 2 study evaluated CAD-1005, a Show less Read more
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