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Stock impact report

Intellia seeks FDA approval for in vivo CRISPR therapy [Yahoo! Finance]

DHI Group, Inc. (DHX) 
Last dhi group, inc. earnings: 2/5 04:15 pm Check Earnings Report
US:NYSE Investor Relations: dhigroupinc.com/investors/default.aspx
Company Research Source: Yahoo! Finance
treatment for hereditary angioedema that would become the first in vivo CRISPR-based gene editing therapy if cleared by regulators. Positive Phase 3 HAELO trial results paved the way for the filing, with lonvo-z cutting the rate of hereditary angioedema attacks by 87% against placebo across a six-month evaluation window, Intellia said. The trial met its primary and all key secondary endpoints. At the six-month mark, 62% of lonvo-z recipients achieved attack-free status without other therapies, compared with only 11% of placebo patients, according to Biospace Regarding safety, Intellia characterized the lonvo-z tolerability data as "favorable," with infusion-related reactions, headaches, and fatigue among the most common adverse events. No serious side effects emerged, and the company disclosed no instances of liver toxicity. Liver safety had been a focus for analysts following a patient death in a separate trial of a different Intellia treatment. That patient was participating i Show less Read more
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