BridgeBio Calls Off Its Acquisition Offer for Eidos Therapeutics [The Motley Fool]
EIDOS THERAPEUTICS (EIDX)
Last eidos therapeutics earnings: 10/31 04:30 pm
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Source: The Motley Fool
BridgeBio Calls Off Its Acquisition Offer for Eidos Therapeutics Eidos Therapeutics ( NASDAQ:EIDX BridgeBio Pharma NASDAQ:BBIO Image Source: Getty Images. Eidos focuses on rare misfolding diseases AG0, Eidos' sole drug candidate, targets the manifestations of a rare disease called transthyretin (TTR) amyloidosis. Transthyretin, an abundant protein that transports thyroxine and retinol, can become misfolded due to genetic or environmental factors. Misfolded proteins often clump together, causing toxic aggregates. When misfolded TTR accumulates in the heart, it causes cardiomypathy (heart disease); TTR aggregation can also lead to polyneuropathy, which damages peripheral nerves. AG0 stabilizes the TTR protein to prevent it from misfolding into a toxic conformation. Eidos management claims that roughly 00,000 people worldwide have TTR cardiomyopathy, a progressive and fatal disease. Pfizer NYSE:PFE approval in May A pivotal clinical trial is under way In April, Eidos kicked off a 0-patie
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